Paliperidone: What it is and how to use it


Paliperidone: What it is and how to use it

What is paliperidone?

Paliperidone is an antipsychotic medication that is utilized to deal with schizophrenia in teenagers as well as grownups who are at the very least 12 years old.

Paliperidone is a psychiatric medication that has been prescribed by doctors for many years. It is also one of the most common antipsychotics on the market today. This article will discuss how to use paliperidone, why it’s used, and who should take it.

Paliperidone might likewise be made use of for functions not listed in this drug guide.


Paliperidone is not approved for usage in older adults with dementia-related psychosis.

Prior to taking this medicine

If you are sensitive to paliperidone or risperidone (Risperdal), you should not make use of paliperidone.

Paliperidone might boost the threat of fatality in older adults with dementia-related psychosis and is not approved for this usage.

High doses or long-lasting use of paliperidone can cause a severe activity problem that may not be reversible. The longer you utilize paliperidone, the more probable you are to create this disorder, especially if you are a lady or an older grownup.

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Tell your doctor if you have actually ever had:

  • heart issues, or a cardiac arrest.
  • long QT disorder (in you or a member of the family), high or low high blood pressure, or fainting spells.
  • low white blood cell (WBC) counts.
  • a significant neurologic disorder triggered by taking an antipsychotic medication.
  • uncontrolled muscle motions in your face.
  • a belly or intestinal tract disorder.
  • liver or kidney illness.
  • seizures or epilepsy.
  • an electrolyte discrepancy (such as low potassium or magnesium levels in your blood).
  • diabetes mellitus (paliperidone might increase your blood sugar); or. breast cancer.

If you are expecting or plan to end up being expecting while utilizing this medicine, inform your medical professional.

Taking antipsychotic medication in the last 3 months of pregnancy may cause breathing troubles, feeding problems, or withdrawal symptoms in the newborn. However, you may have withdrawal symptoms or various other problems if you quit utilizing your medicine while pregnant. If you get pregnant, inform your physician right away. Do not stop using paliperidone without your medical professional’s suggestions.

Your name might be detailed on a pregnancy pc registry to track the effects of paliperidone on the baby if you are pregnant.

It might not be risk-free to breastfeed while using this medicine. Ask your medical professional regarding any kind of threat.

How should I take paliperidone?

Follow all directions on your prescription label and check out all medicine guides or guideline sheets. Make use of the medication specifically as directed.

You may take paliperidone with or without food.

Ingest the tablet whole and also do not squash, chew, or damage it.

Your doctor will certainly require you to examine your development on a regular basis.

Shop at area temperature level far from light, wetness, as well as warmth.

What will happen if I miss out on a dosage?

Take the medicine as quickly as you can, yet miss the missed out on dosage if it is practically time for your next dosage. Do not take two doses at once.

Get your prescription replenished prior to you running out of medication totally.


Medicine interactions might change exactly how your drugs function or raise your risk for significant side effects. This paper does not include all feasible medicine communications. Maintain a checklist of all the items you utilize (consisting of prescription/nonprescription medications and also organic products) and also share it with your physician as well as pharmacist. Do not begin, quit, or transform the dosage of any medications without your physician’s approval.

A product that might interact with this drug is: metoclopramide.

Numerous medicines besides paliperidone may impact the heart rhythm (QT prolongation), including amiodarone, chlorpromazine, moxifloxacin, quinidine, sotalol, procainamide, thioridazine, to name a few.

Tell your medical professional or pharmacist if you are taking various other products that cause sleepiness such as opioid pain or cough reducers (such as codeine, hydrocodone), alcohol, marijuana (marijuana), medicines for sleep or anxiousness (such as alprazolam, lorazepam, zolpidem), muscle depressants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Because they may consist of ingredients that cause drowsiness, check the tags on all your medicines (such as allergy or cough-and-cold products). Ask your pharmacist regarding making use of those items securely.

What happens if I overdose?

Seek emergency clinical focus or call the Poison Help line.

Overdose symptoms might include severe drowsiness, rapid heartbeats, and also fainting.

Telephone call 911 if someone has actually overdosed as well as has severe signs such as passing out or problem breathing. Otherwise, call a poisonous substance control center right now. Canada residents can call a provincial toxin control. Signs of overdose might consist of: extreme drowsiness/dizziness, fast/irregular heart beat, unusual/uncontrolled motions.


Do not share this medicine with others.

Lab and/or medical tests (such as blood sugar level, weight, blood pressure, blood cholesterol/triglyceride levels) must be carried out regularly to monitor your progress or check for side effects. Consult your physician for more details.

Missed Dose

If you miss out on a dosage, take it as soon as you bear in mind. Take your following dose at the regular time.


Shop at space temperature away from light and also dampness. Do not shop in the restroom. Maintain all medicines away from children and pet dogs.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Effectively discard this item when it is run out or no longer needed. Consult your pharmacist or neighborhood garbage disposal company.

What should I prevent while taking paliperidone?

While you are taking paliperidone, you might be extra sensitive to heat. Prevent getting also hot, or coming to be overheated or dehydrated. Drink lots of liquids, specifically in heat and throughout the workout. It is much easier to end up being dangerously overheated as well as dehydrated while you are taking paliperidone.

Stay clear of drinking alcohol. Dangerous adverse effects could take place.

Avoid driving or unsafe activity until you recognize just how paliperidone will certainly impact you. Lightheadedness or drowsiness can create falls, crashes, or extreme injuries.

Avoid rising as well fast from a lying or resting placement, or you might really feel lightheaded.

Paliperidone side effects

Get emergency situation clinical aid if you have indications of an allergy: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Quit taking paliperidone and also call your medical professional at the same time if you have any of these indications of a serious movement problem:.

Unchecked muscular tissue activities in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye activity); or any new or unusual muscle mass movements you can not regulate.

  • quick or pounding heartbeats, fluttering in your upper body, lack of breath, and also sudden lightheadedness (like you might pass out);.
  • breast swelling (in guys or ladies), nipple discharge;.
  • modifications in menstrual periods;.
  • impotence, penis erection that hurts or lasts 4 hours or longer;.
  • weight gain;.
  • low white blood cell counts– fever, cools, mouth sores, skin sores, sore throat, cough, trouble breathing;.
  • high blood glucose– boosted thirst, raised urination, appetite, fruity breath smell; or.
  • extreme nervous system response– very stiff (rigid) muscular tissues, high fever, rapid or battering heart beats, fainting.

Common side effects may include:

  • drowsiness.
  • anxiousness.
  • muscle mass tightness, shakes or trembling.
  • unrestrained muscle activities, problems with strolling, balance, or speech.
  • weight gain.
  • upset stomach, constipation;.
  • quickly heart rate; or.
  • stuffy nose, aching throat.

What other drugs will influence paliperidone?

Making use of paliperidone with other medications that make you dizzy or lower your high blood pressure can aggravate these effects. Ask your doctor before using opioid medicine, a sleeping pill, a muscular tissue relaxer, or medicine for stress and anxiety or seizures.

In some cases it is not secure to make use of specific medications at the same time. Some medications can impact your blood levels of other medications you take, which may increase side effects or make the drugs much less effective.

Numerous medicines can influence paliperidone. Inform your medical professional about all your existing medications and also any kind of medicine you begin or stop using.

Additional information.

Remember, keep this and all other medicines out of the reach of children, never ever share your medications with others, as well as utilize this drug just for the indicator recommended.

Constantly consult your doctor to ensure the info showed on this page applies to your individual circumstances.

Do not quit utilizing paliperidone without your doctor’s advice.

While you are taking paliperidone, you might be extra delicate to warmth. It is easier to become alarmingly overheated and dehydrated while you are taking paliperidone.

Lots of medications can influence paliperidone. Tell your doctor about all your present medicines as well as any type of medicine you start or quit making use of.

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